There's no inherent meaning in information — it's what we do with that information that matters.
Raw information, like a number, a sound, or a flash of light, arrives without any built-in significance. Meaning appears only when a mind interprets it, and the interpretation depends on that mind's history, expectations, and goals. Beau Lotto is a neuroscientist who studies perception, and the idea fits his broader view that the brain does not simply record the world. Light hitting the eye is ambiguous, so the brain makes a useful guess based on past experience. The same signal can look like different things to different people, which is why optical illusions work so well as demonstrations. The idea also echoes an old distinction in information theory, where measuring a message is separate from understanding what it means, and it has some kinship with Kant's claim that experience is shaped by the mind receiving it.
In daily life, think of a short text from your manager saying, "Can we talk tomorrow?" The words carry no verdict. If you assume the worst, you may lose a night's sleep. If you pause and consider other readings, you might prepare calmly and ask a simple question. The information is the same either way, and what changes is what you do with it.